In DNA dynamic nanotechnology, a toehold-mediated DNA strand-displacement reaction has demonstrated its capability in building complex autonomous system. In most cases, the reaction is performed in pure DNA solution that is essentially a one-phase system. In the present work, we systematically investigated the reaction in a heterogeneous media, in which the strand that implements a displacing action is conjugated on gold nanoparticles. By monitoring the kinetics of spherical nucleic acid (SNA) assembly driven by toehold-mediated strand displacement reaction, we observed significant differences, i.e., the abrupt jump in behavior of an “off/on switch”, in the reaction rate when the invading toehold was extended to eight bases from seven bases...
Dynamic DNA nanotechnology often uses toehold-mediated strand displacement for controlling reaction ...
Dynamic DNA nanotechnology often uses toehold-mediated strand displacement for controlling reaction ...
A combination of gold nanoparticles (AuNPs) and nucleic acids has been used in biosensing applicatio...
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the study and applic...
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the study and applic...
The uniquely predictable and controllable binding mechanism of DNA strands has been exploited to con...
<div><p>DNA is increasingly being used as an ideal material for the construction of nanoscale struct...
Surface-immobilization of molecules can have a profound influence on their structure, function and d...
DNA is increasingly being used as an ideal material for the construction of nanoscale structures, ci...
The ability to generate precisely designed molecular networks and modulate the surrounding environme...
Hybridization of DNA strands can be used to build molecular devices, and control of the kinetics of ...
A combination of gold nanoparticles (AuNPs) and nucleic acids has been used in biosensing applicatio...
Raw data, results, and Matlab scripts used for this publication. See README for more information. T...
Dynamic DNA nanotechnology often uses toehold-mediated strand displacement for controlling reaction ...
Toehold-mediated strand displacement has proven extremely powerful in programming enzyme-free DNA ci...
Dynamic DNA nanotechnology often uses toehold-mediated strand displacement for controlling reaction ...
Dynamic DNA nanotechnology often uses toehold-mediated strand displacement for controlling reaction ...
A combination of gold nanoparticles (AuNPs) and nucleic acids has been used in biosensing applicatio...
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the study and applic...
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the study and applic...
The uniquely predictable and controllable binding mechanism of DNA strands has been exploited to con...
<div><p>DNA is increasingly being used as an ideal material for the construction of nanoscale struct...
Surface-immobilization of molecules can have a profound influence on their structure, function and d...
DNA is increasingly being used as an ideal material for the construction of nanoscale structures, ci...
The ability to generate precisely designed molecular networks and modulate the surrounding environme...
Hybridization of DNA strands can be used to build molecular devices, and control of the kinetics of ...
A combination of gold nanoparticles (AuNPs) and nucleic acids has been used in biosensing applicatio...
Raw data, results, and Matlab scripts used for this publication. See README for more information. T...
Dynamic DNA nanotechnology often uses toehold-mediated strand displacement for controlling reaction ...
Toehold-mediated strand displacement has proven extremely powerful in programming enzyme-free DNA ci...
Dynamic DNA nanotechnology often uses toehold-mediated strand displacement for controlling reaction ...
Dynamic DNA nanotechnology often uses toehold-mediated strand displacement for controlling reaction ...
A combination of gold nanoparticles (AuNPs) and nucleic acids has been used in biosensing applicatio...